Reactivity of selected markers of innate and adaptive immunity in rabbits experimentally infected with antigenic variants of RHD (Lagovirus europaeus/GI.1a)

CC BY Logo DOI

Lagovirus europaeus/GI.1 causes a fatal viral condition in rabbits characterized by acute viral hepatitis and disseminated intravascular coagulation. Due to rapid viral and environmental changes variants (Lagovirus europaeus/GI.1a and GI.2) have appeared and few immunological studies were performed. The aim of the study was to determine innate and adaptive immunity parameters in rabbits infected with six Lagovirus europeus/GI.1a viruses. To achieve the goal several methods were used, i.e. cytometry, microscopy, biochemical and cytochemical tests, spectrophotometry. The results show that three immunotypes exists among the studied strains and they differ in innate (mainly) and adaptive immunity, partly depending on hemagglutination. The peak of changes is 24 h post infection in phagocytosis markers of polymorphonuclear cells and CD8+ T cells. Lagovirus europaeus/GI.1a strains differ from Lagovirus europaeus/GI.1 in terms of immunological response based on our previous work concerning the same parameters in immunological response against this disease.

Tytuł
Reactivity of selected markers of innate and adaptive immunity in rabbits experimentally infected with antigenic variants of RHD (Lagovirus europaeus/GI.1a)
Twórca
Niedźwiedzka-Rystwej Paulina Marta ORCID 0000-0003-4065-3842
Słowa kluczowe
rabbit; viral infection; RHDV; RHDVa; Lagovirus europeus; królik; infekcja wirusowa
Współtwórca
Tokarz-Deptuła Beata ORCID 0000-0001-8308-7284
Deptuła Wiesław ORCID 0000-0001-5367-7670
Data
2021
Typ zasobu
artykuł
Identyfikator zasobu
DOI 10.1007/s11259-021-09851-x
Źródło
Veterinary Research Communications, 2021, vol. 46, pp. 233-242
Język
angielski
Prawa autorskie
CC BY CC BY
Dyscyplina naukowa
Dziedzina nauk ścisłych i przyrodniczych; Nauki biologiczne
Kategorie
Publikacje pracowników US
Data udostępnienia1 mar 2023, 09:06:24
Data mod.1 mar 2023, 09:06:24
DostępPubliczny
Aktywnych wyświetleń0