Peripheral blood lymphocytes B and T and their subpopulations in rabbits infected with rabbit haemorrhagic disease virus (RHDV)

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The paper describes the assessment of B lymphocytes with CD19+ receptor, as well as T lymphocytes with receptor CD5+, and their subpopulations – T lymphocytes with CD4+, CD8+, CD25+ receptors, in rabbits infected with seven haemagglutinating strains of RHDV from various European countries. The aim of the study was to find out if the newly observed strains carry the same or similar immunological properties as the RHDV strains analysed previously. The study was performed on 70 mixed-breed rabbits divided into 7 groups of infected animals (consisting of 5 animals each), corresponding to the analyzed RHDV strains. For each of seven groups of infected animals a corresponding group of control animals was assigned (consisting of 5 animals each). The dynamics of the chosen lymphocytes and their subpopulations was assessed with the use of flow cytometry and monoclonal antibodies. The results of the study enable the authors to conclude that those 7 strains resemble Czech strains and may be qualified as strains with medium immunogenicity, forming one immunotype. Keywords: rabbit haemorrhagic disease virus, lymphocytes, immunotypes.

Tytuł
Peripheral blood lymphocytes B and T and their subpopulations in rabbits infected with rabbit haemorrhagic disease virus (RHDV)
Twórca
Niedźwiedzka-Rystwej Paulina ORCID 0000-0003-4065-3842
Słowa kluczowe
rabbit haemorrhagic disease virus; lymhocytes; immunotypes
Słowa kluczowe
wirus pomoru królików; limfocyty; immunotypy
Współtwórca
Tokarz-Deptuła Beata ORCID 0000-0001-8308-7284
Hukowska-Szematowicz Beata ORCID 0000-0002-2776-2799
Działo Joanna
Trzeciak-Ryczek Alicja ORCID 0000-0003-4740-9471
Deptuła Wiesław ORCID 0000-0001-5367-7670
Data
2013
Typ zasobu
artykuł
Źródło
Medycyna Weterynaryjna = Veterinary Medicine, 2013, ann. 69 no. 8, pp. 484-487
Język
angielski
Prawa autorskie
CC BY-SA CC BY-SA
Kategorie
Publikacje pracowników US
Data udostępnienia4 kwi 2023, 12:26:20
Data mod.4 kwi 2023, 12:26:20
DostępPubliczny
Aktywnych wyświetleń0