The paper describes the assessment of B lymphocytes with CD19+ receptor, as well as T lymphocytes with receptor CD5+, and their subpopulations – T lymphocytes with CD4+, CD8+, CD25+ receptors, in rabbits infected with seven haemagglutinating strains of RHDV from various European countries. The aim of the study was to find out if the newly observed strains carry the same or similar immunological properties as the RHDV strains analysed previously. The study was performed on 70 mixed-breed rabbits divided into 7 groups of infected animals (consisting of 5 animals each), corresponding to the analyzed RHDV strains. For each of seven groups of infected animals a corresponding group of control animals was assigned (consisting of 5 animals each). The dynamics of the chosen lymphocytes and their subpopulations was assessed with the use of flow cytometry and monoclonal antibodies. The results of the study enable the authors to conclude that those 7 strains resemble Czech strains and may be qualified as strains with medium immunogenicity, forming one immunotype. Keywords: rabbit haemorrhagic disease virus, lymphocytes, immunotypes.
|Data udostępnienia||4 kwi 2023, 12:26:20|
|Data mod.||4 kwi 2023, 12:26:20|