Immunological memory cells

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This article reviews immunological memory cells, currently represented by T and B lymphocytes and natural killer (NK) cells, which determine a rapid and effective response against a second encounter with the same antigen. Among T lymphocytes, functions of memory cells are provided by their subsets: central memory, effector memory, tissue-resident memory, regulatory memory and stem memory T cells. Memory T and B lymphocytes have an essential role in the immunity against microbial pathogens but are also involved in autoimmunity and maternal-fetal tolerance. Furthermore, the evidence of immunological memory has been established for NK cells. NK cells can respond to haptens or viruses, which results in generation of antigen-specific memory cells.

T, B and NK cells, which have a role in immunological memory, have been characterized phenotypically and functionally. During the secondary immune response, these cells are involved in the reaction against foreign antigens, including pathogens, and take part in autoimmune diseases, but also are crucial to immunological tolerance and vaccine therapy.

Tytuł
Immunological memory cells
Twórca
Ratajczak Weronika
Słowa kluczowe
immunological memory; memory T cells; memory Bcells; memory NK cells
Współtwórca
Niedźwiedzka-Rystwej Paulina ORCID 0000-0003-4065-3842
Tokarz-Deptuła Beata ORCID 0000-0001-8308-7284
Deptuła Wiesław ORCID 0000-0001-5367-7670
Data
2018
Typ zasobu
artykuł
Identyfikator zasobu
DOI 10.5114/ceji.2018.77390
Źródło
Central-European Journal of Immunology, 2018, vol. 43 no. 2, pp. 194-203
Język
angielski
Prawa autorskie
CC BY-NC-SA CC BY-NC-SA
Kategorie
Publikacje pracowników US
Data udostępnienia15 mar 2023, 14:40:18
Data mod.15 mar 2023, 14:40:18
DostępPubliczny
Aktywnych wyświetleń0