Lymphocytes T and B in rabbits infected with RHD virus

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The aim of this study was to determine the differences in immunological response of animals infected with different antigenic variants of the virus – three haemagglutinating (Vt97, Triptis, Hartmannsdorf) and two non-haemagglutinating (Pv97, 9905 RHDVa). The specific immunological response was measured by the dynamics of changes in the amount of lymphocytes T (with CD5+, CD4+, CD8+, CD25+ receptor) and B (with CD19+ receptor). The study showed differences in immunogenicity of the analysed RHDV antigenic variants, which allowed them to be divided into groups of: more immunogenic strains, including non-haemagglutinating 9905 RHDVa and haemagglutinating Vt97 and Triptis variants; and less immunogenic strains, including the haemagglutinating Hartmannsdorf variant and the non-haemagglutinating Pv97 variant. Such a result may indicate that the agglutination capacity of red blood cells might not be a factor impacting the number of T and B lymphocytes.

Tytuł
Lymphocytes T and B in rabbits infected with RHD virus
Twórca
Niedźwiedzka-Rystwej Paulina ORCID 0000-0003-4065-3842
Słowa kluczowe
rabbit haemorrhagic disease; lymfhocytes; antigenic variants
Słowa kluczowe
wirus pomoru królików; limfocyty; warianty antygenowe
Współtwórca
Tokarz-Deptuła Beata ORCID 0000-0001-8308-7284
Deptuła Wiesław ORCID 0000-0001-5367-7670
Data
2013
Typ zasobu
artykuł
Identyfikator zasobu
DOI 10.2478/pjvs-2013-0077
Źródło
Polish Journal of Veterinary Sciences, 2013, vol. 16 no. 3, pp. 563-565
Język
angielski
Prawa autorskie
CC BY-NC-ND CC BY-NC-ND
Kategorie
Publikacje pracowników US
Data udostępnienia23 mar 2023, 08:26:54
Data mod.23 mar 2023, 08:26:54
DostępPubliczny
Aktywnych wyświetleń0